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Found 4 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50191368'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  31nMAssay Description:Degradation of Her2 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  58nMAssay Description:Upregulation of Hsp70 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  8nMAssay Description:Degradation of Her2 in SKBR3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50191368(17-amino-17-demethoxygeldanamycin hydroquinone hyd...)
Affinity DataEC50:  10nMAssay Description:Upregulation of Hsp70 in SKOV3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed