Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM20771'
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM20771(Benzothiazole analogue, 24 | CHEMBL377371 | diethy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM20771(Benzothiazole analogue, 24 | CHEMBL377371 | diethy...)
Affinity DataEC50:  30nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed