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Found 3 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50023280'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hutchison Medipharma

Curated by ChEMBL
LigandPNGBDBM50023280(CHEMBL3334553)
Affinity DataIC50:  96nMAssay Description:Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hutchison Medipharma

Curated by ChEMBL
LigandPNGBDBM50023280(CHEMBL3334553)
Affinity DataIC50:  120nMAssay Description:Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Hutchison Medipharma

Curated by ChEMBL
LigandPNGBDBM50023280(CHEMBL3334553)
Affinity DataEC50:  9.90nMAssay Description:Inhibition of c-Met kinase (unknown origin) assessed as decrease in phosphorylation of TK substrate-biotin peptide preincubated for 5 to 10 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed