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Found 18 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50146166'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human Hs 746T cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human A549 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human SNU5 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in HUVEC assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human SNU638 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human MKN45 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human EBC1 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human NUGC4 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human COLO205 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human OE33 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human KATO III cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human SNU620 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human SNU668 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human U87MG cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human SNU484 cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50: >1.80nMAssay Description:Inhibition of constitutively activated c-Met phosphorylation in human AGS cells assessed as cell viability after 72 hrs by CCK8 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of c-Met (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50146166(CHEMBL3765306)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of HGF induced c-Met phosphorylation in human A549 cells after 10 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed