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Found 2 Enz. Inhib. hit(s) with Target = 'High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A' and Ligand = 'BDBM86645'
LigandPNGBDBM86645(BC11-38-3 | US9173884, BC11-38-3)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipitation method of Wang et al. (32) using recombinant human PDE11A4, PDE10A1, PDE5A1, PDE6...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM86645(BC11-38-3 | US9173884, BC11-38-3)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro enzyme assays were conducted via the Ba(OH)2 precipiation method using recombinant human PDE1C, PDE3B, PDE5A1, PDE6C, PDE8A, PDE9A2, PDE10A1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed