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Found 3 Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50346201'
TargetHistamine H3 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50346201((4-Isopropyl-piperazin-1-yl)-(6-piperidin-1-ylmeth...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50346201((4-Isopropyl-piperazin-1-yl)-(6-piperidin-1-ylmeth...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from histamine H3 receptor in rat cortical hemispheresMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50346201((4-Isopropyl-piperazin-1-yl)-(6-piperidin-1-ylmeth...)
Affinity DataKd:  6.31nMAssay Description:Antagonist activity at histamine H3 receptor in rat cortical hemispheres assessed as inhibition of forskolin stimulated cAMP accumulation after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed