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Found 4 Enz. Inhib. hit(s) with Target = 'Histamine H3 receptor' and Ligand = 'BDBM50615410'
TargetHistamine H3 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615410(CHEMBL5279080)
Affinity DataKi:  1.20nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from recombinant human histamine H3 receptor expressed in CHO-K1 cells assessed a...More data for this Ligand-Target Pair
Ligand Info
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TargetHistamine H3 receptor(Rattus norvegicus (rat))TBA
LigandPNGBDBM50615410(CHEMBL5279080)
Affinity DataKi:  18nMAssay Description:Displacement of N-alpha-[methyl-3H]-methylhistamine dihydrochloride from Sprague-Dawley rat brain membrane histamine H3 receptor assessed as inhibiti...More data for this Ligand-Target Pair
Ligand Info
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TargetHistamine H3 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615410(CHEMBL5279080)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human histamine H3 receptor expressed in CHO-K1 cells assessed as inhibition of imetit-stimulation ERK1/2 phosphorylation by E...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHistamine H3 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50615410(CHEMBL5279080)
Affinity DataEC50:  0.200nMAssay Description:Inverse agonist activity at recombinant human histamine H3 receptor expressed in CHO-K1 cells preincubated for 10 mins followed by [35S]GTPgammaS add...More data for this Ligand-Target Pair
Ligand Info
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