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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM19135'
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM19135(CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...)
Affinity DataIC50:  1.27E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed