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Found 5 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM249366'
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  3nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetyl-lysine tripeptide as substrate preincubated for 24 hrs followed by substrate addition and measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  3nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  3nMAssay Description:Inhibition of HDAC6 (unknown origin) using acetyl-lysine tripeptide substrate as substrate preincubated for 24 hrs followed by substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  3.70nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM249366(US9464073, 003 | US9884850, Compound 3)
Affinity DataIC50:  3.70nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent