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Found 4 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50027662'
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataIC50:  48nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataEC50:  1.64E+3nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as tubulin acetylation after 17 to 18 hrs by cytoblot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50027662(CHEMBL3338418)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of HDAC6 in human A549 cells assessed as induction of tubulin acetylation after 17 to 18 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed