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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM504545'
TargetHistone deacetylase 6(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM504545((S)?N-(tert-Butyl)-1-(2,5-difluoro-4-(5-(trifluoro...)
Affinity DataIC50:  7.5nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM504545((S)?N-(tert-Butyl)-1-(2,5-difluoro-4-(5-(trifluoro...)
Affinity DataIC50:  7.5nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent