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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 6' and Ligand = 'BDBM50602361'
TargetHistone deacetylase 6(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50602361(CHEMBL5206304)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC6 (1 to 1215 residues) using Z-Lys(Ac)-AMC as substrate preincubated for 90 min...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50602361(CHEMBL5206304)
Affinity DataEC50:  460nMAssay Description:Induction of HDAC6 degradation in human HL-60 cells assessed as hyperacetylation of alpha-tubulin after 6 hrs by Western immunoassayMore data for this Ligand-Target Pair
In DepthDetails PubMed