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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM27187'
TargetHistone deacetylase 8(Homo sapiens (Human))
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM27187(triazole-linked clarithromycin-based compound, 24c)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Adam Mickiewicz University

Curated by ChEMBL
LigandPNGBDBM27187(triazole-linked clarithromycin-based compound, 24c)
Affinity DataIC50:  1.89E+3nMT: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed