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Found 2 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 8' and Ligand = 'BDBM50507688'
TargetHistone deacetylase 8(Homo sapiens (Human))
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  309nMAssay Description:Inhibition of human full-length recombinant HDAC8 expressed in baculovirus infected Sf9 insect cells using fluorogenic peptide RHKAcKAc as substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Annji Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50507688(CHEMBL4550214 | US11535598, Compound 5)
Affinity DataIC50:  376nMAssay Description:The IC50 values for aforementioned compounds against HDACs were determined. HDAC 1 to 11 can be assayed by using acetylated AMC-labeled peptide subst...More data for this Ligand-Target Pair
In DepthDetails US Patent