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Found 3 Enz. Inhib. hit(s) with Target = 'Histone lysine demethylase PHF8' and Ligand = 'BDBM195608'
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  7.70E+3nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of KDM7B (unknown origin) ARTKQTAR(KMe1)STGGKAPRKQLA-NovaTagPEG-biotin/2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Genentech

LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of KDM7B (unknown origin) ARTKQTAR(KMe1)STGGKAPRKQLA-NovaTagPEG-biotin/2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed