Found 2 Enz. Inhib. hit(s) with Target = 'Histone-arginine methyltransferase CARM1' and Ligand = 'BDBM50598020'
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human full length recombinant GST-tagged PRMT4 (2 to 608 residues) using histone H3 as substrate incubated for 20 mins in presence of [...More data for this Ligand-Target Pair
TargetHistone-arginine methyltransferase CARM1(Homo sapiens (Human))
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Institut De G£N£Tique Et De Biologie Mol£Culaire Et Cellulaire
Curated by ChEMBL
Affinity DataKd: 252nMAssay Description:Binding affinity to full length recombinant PRMT4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair