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Found 2 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM190198'
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM190198(EPZ008279 | US9175331, 27)
Affinity DataIC50:  20nMAssay Description:Inhibition of methyltransferase activity of human EZH2 using chicken oligonucleotide as substrate by pull down assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))
Epizyme

Curated by ChEMBL
LigandPNGBDBM190198(EPZ008279 | US9175331, 27)
Affinity DataIC50:  22.3nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
In DepthDetails US Patent