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Found 2 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2 [Y641F]' and Ligand = 'BDBM516831'
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM516831(US11104664, Compound P-2 | US11104664, Compound P-...)
Affinity DataIC50:  24nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-Aldrich,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM516831(US11104664, Compound P-2 | US11104664, Compound P-...)
Affinity DataIC50:  154nMAssay Description:Recombinant PRC2 (EZH2-Y641F) was purchased from Active motif, S-adenosyl-methionine (SAM) and Poly-L-lysine (PLL) were purchased from Sigma-Aldrich,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent