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Found 1 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2 [Y641N]' and Ligand = 'BDBM190225'
TargetHistone-lysine N-methyltransferase EZH2 [Y641N](Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM190225(US9175331, 75)
Affinity DataIC50:  4.10E+3nMpH: 7.6Assay Description:Compound 75 was serially diluted 3 fold in DMSO for 10 points and 1 μL , was plated in a 384 well microtiter plate. Positive control (100% inhib...More data for this Ligand-Target Pair
In DepthDetails US Patent