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Found 2 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM389157'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389157(3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-6- carboni...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Iteos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389157(3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-6- carboni...)
Affinity DataIC50:  1.70E+3nMAssay Description:The compounds of the present invention inhibit the enzymatic activity of human IDO1.To measure enzymatic activity of human IDO1, the reaction mixture...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent