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Found 3 Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM50552949'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50552949(CHEMBL4779248)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50552949(CHEMBL4779248)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as reduction in kynurenine production using L-Tryptophan as substrate incubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50552949(CHEMBL4779248)
Affinity DataIC50:  79nMAssay Description:Inhibition of IDO1 in IFNgamma/LPS stimulated human whole blood assessed as reduction in kynurenine production using tryptophan as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed