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Found
1
Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM514519'
Target
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM514519
(8-(6- (trifluoromethyl)imidazo[1,5- a]pyridin-8-yl...)
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Affinity Data
IC50: 1.02E+3nM
Assay Description:
Recombinant human IDO or TDO was incubated in 50 mM KPO4 (pH 7.0), 0.5 mM EGTA, 0.5 mM EDTA, 0.05% Triton™ X100, 20 mM ascorbate, 10 μM methylen...
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Target Info
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Ligand Info
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US Patent
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