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Found
1
Enz. Inhib. hit(s) with Target = 'Indoleamine 2,3-dioxygenase 1' and Ligand = 'BDBM526970'
Target
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human))
Gilead Sciences
US Patent
Ligand
BDBM526970
(5-(3-(2,3-difluorophenyl)pyrazolo[1,5-a]pyridin 7-...)
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Affinity Data
EC50: 13nM
Assay Description:
To measure IDO1 inhibition in tissue culture, HeLa cells were treated with a test compound in the presence of IFNγ, which induces IDO1 expressio...
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