Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43]' and Ligand = 'BDBM562377'
LigandPNGBDBM562377((rac)-4-chloro-7-{3-[(6-fluoro-1-naphthyl)oxy]prop...)
Affinity DataIC50:  0.400nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM562377((rac)-4-chloro-7-{3-[(6-fluoro-1-naphthyl)oxy]prop...)
Affinity DataIC50:  0.930nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM562377((rac)-4-chloro-7-{3-[(6-fluoro-1-naphthyl)oxy]prop...)
Affinity DataIC50:  0.940nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM562377((rac)-4-chloro-7-{3-[(6-fluoro-1-naphthyl)oxy]prop...)
Affinity DataIC50:  22nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent