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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50006296'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006296(15-(4-Amino-butyl)-6-carboxymethyl-12-(3-guanidino...)
Affinity DataIC50:  2.60nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006296(15-(4-Amino-butyl)-6-carboxymethyl-12-(3-guanidino...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Fibrinogen binding to Fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006296(15-(4-Amino-butyl)-6-carboxymethyl-12-(3-guanidino...)
Affinity DataIC50:  2.80E+3nMAssay Description:The compound was tested for the inhibition of fibrinogen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50006296(15-(4-Amino-butyl)-6-carboxymethyl-12-(3-guanidino...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of ADP-induced platelet aggregation in human platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed