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Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50059697'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059697(7-[2-(3-Carbamimidoyl-phenylamino)-acetylamino]-he...)
Affinity DataIC50:  6.40E+4nMAssay Description:Antagonism of fibrinogen binding to a purified human fibrinogen receptor preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059697(7-[2-(3-Carbamimidoyl-phenylamino)-acetylamino]-he...)
Affinity DataIC50:  6.40E+4nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50059697(7-[2-(3-Carbamimidoyl-phenylamino)-acetylamino]-he...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the platelet GPIIb-IIIa receptor measured as ability to attenuate ADP-induced (fibrinogen-mediated) platelet aggregation in human plate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed