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Found 5 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50065166'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065166((S)-N-((R)-1-Carbamoyl-2-cyclohexyl-ethyl)-3-{2-[e...)
Affinity DataIC50:  28nMAssay Description:Inhibition of radiolabeled fibrinogen binding to activated human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065166((S)-N-((R)-1-Carbamoyl-2-cyclohexyl-ethyl)-3-{2-[e...)
Affinity DataIC50:  97nMAssay Description:Ability of the compound to inhibit the aggregation of fixed human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065166((S)-N-((R)-1-Carbamoyl-2-cyclohexyl-ethyl)-3-{2-[e...)
Affinity DataIC50: >2.35E+6nMAssay Description:Inhibition of HUVEC adhesion to fibrinogen-coated platesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065166((S)-N-((R)-1-Carbamoyl-2-cyclohexyl-ethyl)-3-{2-[e...)
Affinity DataIC50: >2.40E+6nMAssay Description:Inhibition of HUVEC adhesion to fibrinogen-coated platesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50065166((S)-N-((R)-1-Carbamoyl-2-cyclohexyl-ethyl)-3-{2-[e...)
Affinity DataIC50: >2.40E+6nMAssay Description:Inhibition of HUVEC adhesion to fibrinogen-coated platesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed