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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50075566'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075566((S)-3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihyd...)
Affinity DataIC50:  29nMAssay Description:Inhibitory activity against Fibrinogen ReceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075566((S)-3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihyd...)
Affinity DataIC50:  29nMAssay Description:Inhibition of unactivated human platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075566((S)-3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihyd...)
Affinity DataKd:  0.900nMAssay Description:Dissociation constant for unactivated Fibrinogen ReceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50075566((S)-3-{2-[(R)-3-(4-Carbamimidoyl-phenyl)-4,5-dihyd...)
Affinity DataKd:  0.600nMAssay Description:Dissociation constant for activated Fibrinogen ReceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed