Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-1' and Ligand = 'BDBM472684'
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472684(US10836720, HIJ-1018)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472684(US10836720, HIJ-1018)
Affinity DataIC50: <100nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of California San Francisco

Curated by ChEMBL
LigandPNGBDBM472684(US10836720, HIJ-1018)
Affinity DataIC50:  5.05E+3nMAssay Description:The blockade of integrin alpha 5 beta 1 provides a novel target for the treatment of asthma. As shown in FIGS. 1A and 1B, delivery of ATN-161, a low ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent