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Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50161783'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50161783(3-{5-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-indol...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration against alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50161783(3-{5-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-indol...)
Affinity DataIC50:  40nMAssay Description:Inhibition of integrin alphavbeta3 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50161783(3-{5-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-indol...)
Affinity DataIC50:  49nMAssay Description:In vitro inhibition of human alphaV-beta3 integrin binding in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed