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Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-5' and Ligand = 'BDBM50308730'
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto Di Ricerche Chimiche E Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308730(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)
Affinity DataIC50:  0.170nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto Di Ricerche Chimiche E Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308730(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of integrin alphaVbeta5 receptor-mediated adhesion of human A2780 cells to vitronectin after 1 hr by toluidine blue stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Istituto Di Ricerche Chimiche E Biochimiche G. Ronzoni

Curated by ChEMBL
LigandPNGBDBM50308730(4-((2S,5S,11S,14R)-14-benzyl-11-(carboxymethyl)-5-...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of integrin alphaVbeta5 receptor-mediated adhesion of human A498 cells to vitronectin after 1 hr by toluidine blue stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed