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Found 2 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM318829'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM318829(US10517872, Compound 6 | US9624246, Compound 6)
Affinity DataIC50: <100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)).In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM318829(US10517872, Compound 6 | US9624246, Compound 6)
Affinity DataIC50:  550nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)). In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Se...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent