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Found 6 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50040867'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040867(CHEMBL3353206 | US9586948, Example 25)
Affinity DataIC50:  32nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040867(CHEMBL3353206 | US9586948, Example 25)
Affinity DataIC50:  32nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040867(CHEMBL3353206 | US9586948, Example 25)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040867(CHEMBL3353206 | US9586948, Example 25)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040867(CHEMBL3353206 | US9586948, Example 25)
Affinity DataIC50:  138nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040867(CHEMBL3353206 | US9586948, Example 25)
Affinity DataIC50:  138nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair