Found 6 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM50246769' 
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human full-length His-tagged IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length N-terminal His6-tagged human IRAK4 expressed in baculovirus infected Sf21 insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant full length His-tagged human IRAK4 expressed in baculovirus expression system using 5-FAM-IPTSPITTTYFFFKKK-COOH as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of IRAK4 in human KARPAS299 cells assessed as reduction in IL-1 stimulated IRAK4 phosphorylation at Thr345/Ser346 residues preincubated fo...More data for this Ligand-Target Pair
Affinity DataKd: 0.700nMAssay Description:Binding affinity to wild type human IRAK4 (M1 to S460) expressed in mammalian expression systemMore data for this Ligand-Target Pair
