Found 6 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP] cytoplasmic' and Ligand = 'BDBM50522839' TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University
Curated by ChEMBL
Huazhong Agricultural University
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in pres...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University
Curated by ChEMBL
Huazhong Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of N-terminal 6-His-tagged IDH1 R132C mutant (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in pres...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University
Curated by ChEMBL
Huazhong Agricultural University
Curated by ChEMBL
Affinity DataIC50: 4.37E+4nMAssay Description:Inhibition of N-terminal 6-His-tagged wild type IDH1 (unknown origin) expressed in Escherichia coli BL21 cells using alpha-KG as substrate in presenc...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University
Curated by ChEMBL
Huazhong Agricultural University
Curated by ChEMBL
Affinity DataKd: 720nMAssay Description:Binding affinity to N-terminal 6-His-tagged IDH1 R132C mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant ...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University
Curated by ChEMBL
Huazhong Agricultural University
Curated by ChEMBL
Affinity DataKd: 3.80E+3nMAssay Description:Binding affinity to N-terminal 6-His-tagged IDH1 R132H mutant (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant ...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))
Huazhong Agricultural University
Curated by ChEMBL
Huazhong Agricultural University
Curated by ChEMBL
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to N-terminal 6-His-tagged wild type IDH1 (unknown origin) expressed in BL21 cells assessed as equilibrium dissociation constant by ...More data for this Ligand-Target Pair
