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Found 6 Enz. Inhib. hit(s) with Target = 'Isocitrate dehydrogenase [NADP] cytoplasmic [R132C]' and Ligand = 'BDBM363543'
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Servier Pharmaceuticals

US Patent
LigandPNGBDBM363543(US10640534, Compound 35 | US10689414, Compound 35 ...)
Affinity DataIC50: <100nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Servier Pharmaceuticals

US Patent
LigandPNGBDBM363543(US10640534, Compound 35 | US10689414, Compound 35 ...)
Affinity DataIC50: <100nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Servier Pharmaceuticals

US Patent
LigandPNGBDBM363543(US10640534, Compound 35 | US10689414, Compound 35 ...)
Affinity DataIC50:  300nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Servier Pharmaceuticals

US Patent
LigandPNGBDBM363543(US10640534, Compound 35 | US10689414, Compound 35 ...)
Affinity DataIC50:  300nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Servier Pharmaceuticals

US Patent
LigandPNGBDBM363543(US10640534, Compound 35 | US10689414, Compound 35 ...)
Affinity DataIC50:  300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
Servier Pharmaceuticals

US Patent
LigandPNGBDBM363543(US10640534, Compound 35 | US10689414, Compound 35 ...)
Affinity DataIC50: <500nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent