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Found 1 Enz. Inhib. hit(s) with Target = 'Isoform C of Beta-secretase 1 (BACE-I-457)' and Ligand = 'BDBM113403'
TargetIsoform C of Beta-secretase 1 (BACE-I-457)(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM113403(US10336717, Compound 593 | US8633212, 593 | US9212...)
Affinity DataIC50:  6nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
In DepthDetails US Patent