Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'JAK3/JAK1' and Ligand = 'BDBM50507816'
TargetJAK3/JAK1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50507816(Bms-986165 | Deucravacitinib)
Affinity DataIC50:  592nMAssay Description:Inhibition of JAK1/JAK3 in human PBMC assessed as decrease in IL2-induced STAT5 phosphorylation in CD3+ T cells preincubated for 1 hr followed by sti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetJAK3/JAK1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50507816(Bms-986165 | Deucravacitinib)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of JAK1/JAK3 in in human whole blood assessed as decrease in IL2-induced STAT5 phosphorylation in CD3+ T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed