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Found 1 Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM345059'
TargetKallikrein-1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM345059(4-({(2R)-2-[5-(3-chloro- 2,6-difluorophenyl)-1- ox...)
Affinity DataIC50:  18.2nMAssay Description:Kallikrein determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; Fishe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent