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Found
1
Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM345061'
Target
Kallikrein-1
(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Ligand
BDBM345061
(2-{5-[5-chloro-2-(1H- tetrazol-1-yl)phenyl]-1- oxi...)
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Affinity Data
IC50: 1.90nM
Assay Description:
Kallikrein determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; Fishe...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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