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Found
1
Enz. Inhib. hit(s) with Target = 'Kallikrein-1' and Ligand = 'BDBM620030'
Target
Kallikrein-1
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM620030
(Methyl (4-(2-((3S)-7-(3-chloro-2-fluoro-6-(1H-tetr...)
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Affinity Data
IC50: 1.40nM
Assay Description:
A fluorescence intensity (FLINT) based assay was used to monitor inhibition of human plasma kallikrein. The peptide substrate, Z-Gly-Pro-Arg-AMC (Pur...
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Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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