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Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50015009'
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University of Bath

US Patent
LigandPNGBDBM50015009(CHEMBL3262367 | US9259422, 7a, R = 3,5-diMePh- BU1...)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/molepH: 7.4 T: 2°CAssay Description:As Alt et al., 2002. Membranes (20 ug) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presence ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University of Bath

US Patent
LigandPNGBDBM50015009(CHEMBL3262367 | US9259422, 7a, R = 3,5-diMePh- BU1...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]diprenorphine from recombinant human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The University of Bath

US Patent
LigandPNGBDBM50015009(CHEMBL3262367 | US9259422, 7a, R = 3,5-diMePh- BU1...)
Affinity DataKi:  0.100nMpH: 7.4Assay Description:As Alt et al., 2002. Membranes (20 μg) are incubated in 50 mM Tris-HCl, pH 7.4 with [3H]diprenorphine or [3H]nociceptin in the absence or presen...More data for this Ligand-Target Pair
In DepthDetails US Patent