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Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50108441'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50:  56nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50:  56nMAssay Description:Binding affinity for 5-HT3 receptor of NG108-15 cells using [3H]-GR-65,630More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50108441(3-Phenyl-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-p...)
Affinity DataIC50:  56nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed