Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50316611'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]Cl977 from human kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316611((+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]...)
Affinity DataEC50:  1.80E+3nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed