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Found 3 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50316619'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  8.70nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane after 150 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataKi:  70nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50316619((+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8...)
Affinity DataEC50:  820nMAssay Description:Agonist activity at human recombinant kappa opioid receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed