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Found 5 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50399881'
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399881(CHEMBL2180639)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM50399881(CHEMBL2180639)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-HS665 from KOR in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399881(CHEMBL2180639)
Affinity DataEC50:  463nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta-arrestin 2 recruitmentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399881(CHEMBL2180639)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399881(CHEMBL2180639)
Affinity DataEC50:  5nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed