Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM65817'
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataKi:  40nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataIC50: >3.20E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataEC50:  347nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics Source Affiliation: Sanford-Burnham Medical Research Institute Network: NIH Molecular Lib...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataEC50:  867nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataEC50:  870nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitmentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataEC50:  8.99E+3nMAssay Description:Inhibition of rat TRPA1 at a holding potential of 15 mV measured after 1 min by whole-cell manual patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataEC50:  870nMAssay Description:Agonist activity at human kappa opioid receptor expressed in human U2OS cells co-transfected with EFC and beta-arrestin-2 assessed as increase in bet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM65817(2-[5-[(3,4-dichlorobenzyl)thio]-4-(2-furfuryl)-1,2...)
Affinity DataEC50:  1.40E+5nMAssay Description:Inhibition of kappa opioid receptor (unknown origin) assessed as increase in beta arrestin 2 recruitment relative to controlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed