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Found 4 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM97710'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97710(US8476271, 16 | US9145408, 362)
Affinity DataKi:  2.28E+3nM ΔG°:  -32.2kJ/molepH: 7.4 T: 2°CAssay Description:In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97710(US8476271, 16 | US9145408, 362)
Affinity DataKi:  2.28E+3nM ΔG°:  -29.9kJ/molepH: 7.4 T: 2°CAssay Description:Alpha-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97710(US8476271, 16 | US9145408, 362)
Affinity DataKi:  4.76E+3nM ΔG°:  -30.4kJ/molepH: 7.4 T: 2°CAssay Description:In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97710(US8476271, 16 | US9145408, 362)
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Alpha-Opioid Receptor Functional Assay Procedures: Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane...More data for this Ligand-Target Pair
In DepthDetails US Patent