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Found 6 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM97711'
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97711(US8476271, 17 | US8846929, 360 | US8846929, 361 | ...)
Affinity DataKi:  2.69E+3nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4-0.8nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 ug membrane protein (recombinant kappa opioid receptor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97711(US8476271, 17 | US8846929, 360 | US8846929, 361 | ...)
Affinity DataKi:  6.14E+3nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4-0.8nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 ug membrane protein (recombinant kappa opioid receptor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97711(US8476271, 17 | US8846929, 360 | US8846929, 361 | ...)
Affinity DataKi:  6.14E+3nM ΔG°:  -27.7kJ/molepH: 7.4 T: 2°CAssay Description:Alpha-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97711(US8476271, 17 | US8846929, 360 | US8846929, 361 | ...)
Affinity DataKi:  6.14E+3nM ΔG°:  -29.7kJ/molepH: 7.4 T: 2°CAssay Description:In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97711(US8476271, 17 | US8846929, 360 | US8846929, 361 | ...)
Affinity DataKi: >2.00E+4nM ΔG°: >-26.8kJ/molepH: 7.4 T: 2°CAssay Description:In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM97711(US8476271, 17 | US8846929, 360 | US8846929, 361 | ...)
Affinity DataEC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:Alpha-Opioid Receptor Functional Assay Procedures: Functional [35S]GTPgammaS binding assays were conducted as follows. Kappa opioid receptor membrane...More data for this Ligand-Target Pair
In DepthDetails US Patent