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Found 2 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF18A' and Ligand = 'BDBM636941'
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636941(N-(4-(4-(1-(4,4-difluorocyclohexyl)-1H- pyrazol-3-...)
Affinity DataIC50:  5nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKinesin-like protein KIF18A(Homo sapiens)
Volastra Therapeutics

US Patent
LigandPNGBDBM636941(N-(4-(4-(1-(4,4-difluorocyclohexyl)-1H- pyrazol-3-...)
Affinity DataIC50:  8.20nMAssay Description:Test compounds were plated in a 3x dilution scheme in a 384-well plate. Assay buffer: 80 mM PIPES (pH 6.9), 1 mM MgCl2, 75 mM KCl, 1 mM EGTA, 1 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent